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Significant Market Position Toshiba Marketing Essay

Huge Market Position Toshiba Marketing Essay Toshiba is a solid and regarded name in the market with a merited notoriety for advancement,...

Sunday, October 6, 2019

Do journalists have an ethical responsibility towards future audiences Essay

Do journalists have an ethical responsibility towards future audiences as producers of the first draft of history - Essay Example Ethics and journalism have always had an uneasy relationship, James Carey (1987) states that ethics were introduced as an attempt to control journalists, he is of the view that ethics reflect status and class conflict between the owners of the press, the readers and the reporters. Other theories surrounding the emergence of ethics in journalism state that it was an attempt to stop large corporations from giving freebies and junkets to journalists in return for a favourable piece in the press (Christi 1989). In the modern world, journalism ethics are fundamentally governed by the Human Rights; which includes the right to freedom of expression, the right to privacy and the right to information. Society’s expectations of the press and mass media also contribute towards deciding of journalistic ethics. Journalists and the mass media have influential power, which is inherent in their role as informers to the general public. It is their fundamental duty to provide complete informati on, and not distort the picture in any way; however it is easier said than done. Not only are journalists reporters; but they are also human beings, with an opinion. They have a particular view of circumstances,and do not always see the truth; therefore it is important that they carry out their task as objectively as possible and not involve their own opinion- for their opinion can distort the facts . As Wolfgang Donsbach (1992) points that ethical journalism consists of the efforts of finding out complete information, and present the facts in a neutral way. Journalists who state their opinion, and influence facts to back up their opinion are not only unprofessional, but also un-ethical. An opposing view is expressed by Malcom (1989) where he states every journalist... Do journalists have an ethical responsibility towards future audiences as producers of the first draft of history? Information is an increasingly important resource and journalists play a crucial role in producing and disseminating that information. Technology has made broadcasting information easier, which makes information more powerful, and therefore makes journalists the carriers of this power. Journalists have influential power on the public; their views can shape decisions and recollections of past events. Given the freedom of expression, journalists now have the power to hold the government accountable for their misgivings, they are able to raise questions on behalf of the public and subsequently force the government to correct their mistakes. They can make history, alter how we remember history and choose what not to include in history. Journalism, Ethics and Society In a democratic world, journalist have the responsibility of reporting corruption, abuse of power and any other item of information that the public has the right to know. They have a special political purpose to seek the trut h, and resist the pressure to convey distortions. Journalism is indeed a first draft of memory, as Zarecka (1994) states, thatthe elements of the past that are remembered are worth knowing about. Hence journalists must seek to solidify the pieces of information that are deemed to go down in history books, and to conceptualize them by depicting them through mass media.

Saturday, October 5, 2019

What's Wrong With the WikipediaJews in the Middle Ages Entry Essay

What's Wrong With the WikipediaJews in the Middle Ages Entry - Essay Example A number of article entries have made fantastic claims about certain events, people, or facts without providing any authentic or credible sources to back them. Wikipedia is an open and free encyclopedia which is not considered to be a valid and trustworthy source by universities. Students are not allowed to cite information taken from Wikipedia while other schools have banned its usage. This research paper assesses the encyclopedic entry â€Å"Jews in the Middle Ages† by pointing out the untrustworthiness and unreliability of its content. It considers how the article is limited with reference to the history of the Jews by excluding several communities. It also studies how certain elements and aspects of Jewish history have not been added into the entry. The paper investigates and critically assesses how the article makes conclusions regarding the relations between the Jews and majority culture. The article extensively writes about the social conditions of the Jews living in West Europe. It fails to mention the history of the Jews who lived in the Middle East and Russia1. The Islamic caliphates were at the height of their intellectual, scientific, and philosophical achievements. Unlike the Christian West, Jews were actually tolerated and protected under Arab areas. The Jews had to pay a special tax called â€Å"Jizya† which was levied on minorities. Wikipedia’s article fails to write about the social conditions of the Jews in the Islamic caliphates. Jews rose to important positions inside the Islamic Caliphates like Solomon Ibn Gabirol and Yehuda HaLevi2. These Jews made extensive contributions towards the study of Judaism by writing interpretations of the Torah, philosophical beliefs, and prayers. An investigation of the article also reveals little information regarding the position of Jews in the Slavic nations. The Khazar kingdom in the middle ages was a Je wish state in the

Friday, October 4, 2019

Homemade Plastic Baggy Ice Cream Essay Example for Free

Homemade Plastic Baggy Ice Cream Essay Ever really want ice cream but did not feel like going out to get it? Now you can make it at home with no ice cream maker needed to make it. Ice cream is surprisingly easy to make yourself. It is also a fun yet quick process. There are only a few steps in creating this delicious, loved, cold treat. All you need is a few ingredients and to shake, shake, shake! The first thing you will need to do is gather all of the items that you need. To make plastic baggy ice cream you will need the following; sugar, half and half, salt; rock salt works best, vanilla, ice cubes; enough to fill half of the gallon size bag, one pint size Ziploc bag, and one gallon size Ziploc bag. After all of your items are gathered, the sugar, half and half, and salt will all have to be measured out. You will need two tablespoons of sugar, a half teaspoon of vanilla, one cup of half and half, and a half a cup of salt. Once everything is gathered, measured, and ready to go, it is time to get started adding everything together. The first thing you will want to do is open your small, pint size plastic baggy. Next you will want to combine your sugar with the half and half and vanilla all in the plastic bag. Once everything is in the baggy, make sure it is closed and sealed tight. Afterwards, you will need to get the gallon size bag ready. Open your gallon Ziploc bag and fill it about half full with ice. Once the ice is in the baggy, add the half cup of salt right into the gallon bag, over the ice. Before you close your bag, place the sealed, pint size bag in along with the salt and ice. When the pint size bag has been placed into the gallon size, seal the gallon size back tight. After everything is combined into the right baggies and they are sealed tight, it is time to shake. It should take about five minutes or so of continuous shaking to start seeing the difference of the liquid turning into the solid. You want to shake the gallon size bag really well until you can feel the mixture of things in the pint size bag starting to get ice cream textured. Immediately following the shaking of the bag and the pint size bag is starting to harden, carefully open the gallon size bag. Make sure to open the bag carefully because you do not want the ice falling out. Once you have opened the bag, pull the pint size bag out of the gallon size bag. Your ice cream is now ready to eat! You will usually have a single serve size or two serving sizes. In the end, you can add whatever mixings you want to; sugars, sprinkles, chocolate sauce, etcetera. Making ice cream at home is not hard at all and there are only a couple of supplies needed in order to do so! Furthermore, making plastic bag ice cream is a great activity to do especially with kids! It is a fun way to get your children and their friends involved with making their own ice cream and learning measurements. It is a very simple activity. It also gives you a free, all access pass to the delicious treat you love, as well as an easy clean up! All there is to do in the end is simple, dump the ice out of the gallon baggy and throw both bags out.

Thursday, October 3, 2019

Use Of Abiraterone In Castration Resistant Prostate Cancer Nursing Essay

Use Of Abiraterone In Castration Resistant Prostate Cancer Nursing Essay Prostate cancer is the most common type of cancer diagnosis of men in Canada. In 2012, approximately 26,500 men in Canada were diagnosed with prostate cancer and approximately 4,000 died from the disease . Prostate cancer is strongly influenced by androgenic steroids . In advanced stage prostate cancer patients are typically treated using androgen deprivation therapy. . Androgen therapy is not curative and may only improve patients symptoms and may even reduce metastatic lesions . The benefit seen in androgen deprivation is often reduced over years of androgen therapy as the tumour will continue to grow despite low androgen levels. When this occurs the tumour is known to be castration resistant and is known to lead to prostate cancer- related mortality . Castration-resistant prostate cancer (CRPC) may present as either a continuous rise in serum prostate- specific antigen levels (PSA), progression of pre-existing disease, or appearance of new metastases . Many endocrine based therapies have been evaluated for CRPC with minimal success in prolonging patient survival . Systemic nonhormonal therapies using docetaxel, carbaztaxel, and active cellular immunotherapy with sipuleucel-T have been shown to prolong survival . A new drug abiraterone (Zytiga) has shown to improve survival and lower PSA levels in patients with CRPC. This article is to be used by health professionals to gain a thorough understanding of abiraterones indication, mechanism of action, side effects, dosage, clinical evidence, monitoring parameters, and contraindications. Indication According to the product monograph for abiraterone the drug is indicated with prednisone for the treatment of CRPC in patients who have received prior chemotherapy containing docetaxel. Mechanism of Action Abiraterone is formulated as a prodrug, abiraterone acetate, which is converted to abiraterone by the body and acts as a selective inhibitor of 17ÃŽÂ ±-hydroxylase/C17,20-lyase (CYP17) . CYP17 is responsible for androgen biosynthesis in testicular, adrenal and prostatic tumor tissues . As illustrated in Figure 1, CYP17 catalyzes the conversion of pregnolone and progesterone into testosterone precursors, DHEA and androstenedione . The reduction in androgen production is beneficial for androgen-sensitive prostatic carcinoma. 722776-fig1.jpg Figure 1. Abiraterones mechanism of action in androgen synthesis Side Effects The most common side effects of abiraterone are caused by the mechanism of the drug on CYP17. As seen in Figure 2, inhibition of CYP17 causes on increase in the production of mineralocorticoids, which lead to hypokalemia, fluid retention, and hypertension . Other common side effects of abiraterone include myopathy, joint pain, abnormal liver function, hot flashes, diarrhea, urinary tract infections, bone fractures and cough . http://jco.ascopubs.org/content/28/9/1481/F4.large.jpg Figure 2. Effects of abiraterone on mineralocorticoid production . Dosage and Administration The recommended dosage of abiraterone is 1000 milligrams daily as a single dose . The tablets need to be swallowed whole and the dose should be taken on an empty stomach . To reduce the mineralocorticoid effects of abiraterone the patient should also use a low dose prednisone. The recommended dose or prednisone is 10 mg daily . Clinical Trials Evaluating Abiraterone The effectiveness of abiraterone in CRPC has been demonstrated in several randomized trials. In 2009, a study Attard et al., using forty-two chemotherapy-naÃÆ' ¯ve patients with CRPC received 1000 mg abiraterone . At follow up (median 505 days) a decline in PSA of à ¢Ã¢â‚¬ °Ã‚ ¥ 50% of was observed in 67% of patients, with declines of à ¢Ã¢â‚¬ °Ã‚ ¥ 90% in 19% of patients . A 2010 study by Danila et al., of fifty-eight men with CRPC previously on docetaxel received abiraterone 1000 mg daily with 5 mg of prednisone . Results of study illustrated that 36 % of patients had a PSA decline of à ¢Ã¢â‚¬ °Ã‚ ¥ 50% . In 2011, De Bono et al. conducted a study including 1195 patients who had previously received docetaxel . Groups were assigned in a 2:1 ratio to receive 5 mg of prednisone twice daily with either 1000 mg of abiraterone or placebo . The primary end point of the study was overall survival . The secondary endpoints of the study were time to prostate-specific antigen progression, progression-free survival according to radiological findings based on specified criteria, and PSA response rate . At a median 12.8 month follow-up overall survival was significantly longer in the abiraterone group compared to the placebo (14.8 months vs. 10.9 months, p. The secondary end points all favoured the treatment group; time to PSA progression (10.2 vs. 6.6 months; p. The studies using abiraterone in CRPC illustrate that the drug provides a moderate improvement in cancer progression and improves survival in patients. Monitoring Parameters Health professionals should place on emphasis of monitoring patients using abiraterone. Before treatment hypokalemia and hypertension must be normalized in patients who are scheduled to use the drug . It is important to routinely monitoring a patients blood pressure while they are on this product. Potassium levels should be checked at baseline and regularly to prevent hypokalemia in patients. Patients should also be checked for signs of fluid retention, such as peripheral edema. Liver function tests (ALT, AST, and bilirubin) should be measured prior to initiating abiraterone treatment and continued every two weeks for the first three months of treatment and monthly afterwards . Patients should routinely be assessed for other common side effects, including joint pain and urinary tract infections. Conclusion CRPC is a very advanced stage of prostate cancer that is fatal. Abiraterone (Zytiga) has been shown to prolong survival and lower PSA in men with CRPC. The drug works by selectively inhibiting CYP17 and lowering the production of testosterone via upstream inhibition of precursors in prostate, adrenal, testicular tissues. The selective inhibition of CYP17 leads to a large increase in mineralocorticoid activity in the body leading to hypertension, edema, and hypokalemia. The excess mineralocorticoid activity is typically diminished by administering 10 mg of prednisone daily with abiraterone. It is important to note that abiraterone is indicated as a second line therapy for patients who have failed treatment with docetaxel. While on abiraterone patients need to be monitored for hepatic function, hypertension, hypokalemia, and edema. .

Wednesday, October 2, 2019

Alienation in Tennessee Williams, The Glass Menagerie Essay -- Tennes

Alienation in Tennessee Williams', The Glass Menagerie Life is a lonely tale of alienation, as Tennessee Williams conveys though his play, â€Å"The Glass Menagerie.† Williams surrounds Laura in isolation from a world in which they wish to belong to by using various symbols. The symbolic nature of the motifs hidden within the lines of this play provides meaning to the theme found consistent throughout the play: Individuals are all alone in the world. Williams brilliantly illuminates the idea of isolation through the symbolic use of glass. The symbolism of the glass is directly connected with the character of Laura. Similar to glass Laura is extremely fragile, her soul and image faces the possibility of being easily damaged and destroyed. Her character is tragically transparent as it is simple to decipher. However, glass objects, unlike a painting or photograph, have three dimensions. It is possible to examine every side of Laura’s fragile character, just as it is a glass figurine. Laura is trapped into a mold of glass, unable to move or break from its pattern; she is trapped in her own world of alienation. Yet, in a different light, glass reflects a rainbow of personality and beauty. Similar to the rainbow given off by glass Laura aids characters in achieving a sense of beautiful and colorful self-awareness. Williams contrasts light and dark to bring attention to Laura’s isolation from the world, and illuminate it as moments of the beauty that exists in huma...

Packaging :: essays research papers

Successful and Unsuccessful Packages   Ã‚  Ã‚  Ã‚  Ã‚  Budweiser package and Foster package does more than they contain and protect products. They also tell their great deal about the people from different countries that buy the products, as well as the people from different countries who sell the products. In addition, both packages are made in different countries, and both packages have differences and similarities.   Ã‚  Ã‚  Ã‚  Ã‚  Budweiser package is manufacture in America and contains various bottle sizes and various can sizes. Budweiser bottle is small and easy to hold and the cap is easy to open. In addition, it is made in thick glass so when it drops from the knee down it does not crack, and it ¡Ã‚ ¯s appearance is attractive to people. Budweiser can is made in different beer quantity from 6 ounces to 24 ounces. Moreover, it encloses different item quantity from case of 6 to case of 24.   Ã‚  Ã‚  Ã‚  Ã‚  On the other hand, Foster package is manufacture in Australia and contains one bottle size and one can size. Foster bottle is large and hard to hold and it is hard to open. In addition, it is made in thin glass so it ¡Ã‚ ¯s easy to break when it drops. Foster can contains only one beer quantity, which is 6 ounces and doesn ¡Ã‚ ¯t enclose various options to meet people preferences. In addition, Foster only has one item quantity, which is case of 6 that most people prefer case of 24. Budweiser package is a successful selling product in America because the price of the products is affordable to buy and it on advertisement (billboard, radio, and TV). In addition, the company and the product are popular to US citizen. Besides, Budweiser alcohol level is low around .02, which most American prefers that level of alcohol to be. For example, in New York Time Magazine say most American like to drink Budweiser because they say it tastes better and the alcohol level is no t dangerous for driving. On the other side, Budweiser package is a failure in Australia because it considers a foreign product and Australian prefers to have higher alcohol level.   Ã‚  Ã‚  Ã‚  Ã‚  Foster package is a failure in the United State for the reason that it ¡Ã‚ ¯s a foreign product and doesn ¡Ã‚ ¯t meet US citizen preferences. In addition, it contains lack in advertising and contains high alcohol level. Besides, Foster company and products are unpopular in the US, so the percentage of selling the product really low.

Tuesday, October 1, 2019

Aids Treatments

Aids is one of the most threatening disease which is effecting the lives of many people around the globe, plus the most astonishing fact is that it is effecting people and spreading at an exponential rate and as public awareness programs focus on it The most disturbing fact is that as the number of cases double a cures not in sight nor a vaccine has been developed and Aids is still an incurable condition.The human immunodeficiency virus has a direct and a lethal on life, at its very core, the transmission occurs principally via blood, semen and â€Å"vaginal fluid other bodily fluids, like the saliva, contain far too low a concentration of the virus to be dangerous Both blood and semen signify life and potential life in a concrete way.† (Paskin, 1994)AIDS is the most severe stage, of the infection with what we know as the AIDS virus. AIDS is also generally accepted as a syndrome, a collection of specific, life-threatening and dangerous signs that is due to an underlying immune deficiency, a deficiency not caused by any known conditions and illnesses other than infection with the AIDS virus.It destroys the body's capacity to ward off bacteria and viruses that would ordinarily be fought off by a properly functioning immune system, and it is the diseases, the opportunistic infections, caused by these outside agents that eventually kill the victim; or, death results from a form of cancer, Kaposi's sarcoma, that is far more aggressive in AIDS patients than among those who do not suffer from AIDS.Thus, one can say that AIDS killed the person, since the addition of the ‘S’ defines a syndrome: the collection of diseases and symptoms that resulted from the weakened immune system.Putting it another way, one can say that the â€Å"AIDS virus itself does not kill, nor does it generally cause the various diseases associated with the syndrome; most of the disastrous events are simply the result of the damage to the immune system.† (Elli, 1992)The t reatment of HIV-related immunological and neurological disease involves the control of HIV replication by specific anti-viral drugs, boosting the host's own immune response to HIV, dampening down any potentially harmful results of the immune response, and reconstituting the defective cell-mediated immunity.Thus, a broad range of approaches are being tried. This in some way reflects the uncertainty regarding the pathogenesis of this infection. The management of the specific opportunist infections and tumors that arise because of the immunodeficiency are covered in Chapter 4.Here, we will focus on the treatment of the underlying HIV infection. The ultimate goal for the HIV-infected person would be the eradication of HIV infection. However, this is unlikely to be achieved as the virus integrates into the host chromosome, and therefore all infected cells would have to be removed.This may be possible in renewable tissue, such as lymphoid cells, but not within the nervous system, where ce lls cannot be replaced. However, if the virus could be suppressed to the level where it is not damaging the host or continuing to infect new cells, then the disease process may be halted.The virus can potentially be inhibited in three ways: (1) by preventing binding or fusion to the target cell; (2) by inhibiting replication and release; and (3) by inducing non-infective particlesDespite many public health efforts and programs for the awareness of the disease around the globe it is still seen that in many underdeveloped countries Aids awareness programs do not work and people are still indulging into acts like prostitution and unsafe sexual activities.So therefore to address this issue governments in these countries have conducted many health programs such as making people aware about the effects of the disease and   raising more informational sessions for people indulging into behaviors which are a main source in spreading this virus.Now governments around the worlds are funding projects which are related to the disease so that the people at large do not get affected by the disease.These public health efforts around the world especially in Asian and African countries has led to people becoming more aware of the hazards of the aids epidemic and because of these health awareness programs people to not indulge into unprotected sexual behavior.Works CitedPaskin, J. M. HIV and AIDS. Publisher: Bios Scientific Publishers. Place of Publication: Oxford, England. Publication Year: 1994.Elli, Ottoman. HIV Infection and Intravenous Drug Use. Publisher: Praeger Publishers. Place of Publication: Westport, CT. Publication Year: 1992